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Last Updated: March 26, 2026

Claims for Patent: 5,994,409


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Summary for Patent: 5,994,409
Title:Methods for treatment of neuro--and nephro--disorders and therapeutic toxicities using aminothiol compounds
Abstract:The present invention relates to new uses of S-2-(3-aminopropylamino)ethyl dihydrogen phosphorothioate, (amifostine) and other aminothiol compounds to treat and reverse toxicities caused by therapeutic agents, radiation treatment or diabetes. In particular, the invention provides a method for treating neurotoxicity and nephrotoxicity associated with the administration of chemotherapeutic agents.
Inventor(s):Martin Stogniew, David S. Alberts, Edward H. Kaplan
Assignee:ARIZONA UNIVERSITY OF ARIZONA BOARD OF REGENTS ON BEHALF OF, Clinigen Group PLC, University of Arizona
Application Number:US08/987,550
Patent Claims:

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