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Claims for Patent: 5,993,830

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Claims for Patent: 5,993,830

Title: Cosmetic skin preparation
Abstract:The present invention relates to a skin preparation comprising lipophilic and hydrophilic components, which is intended for application on skin. The skin preparation according to the present invention is characterized in that it exists as a two-phase system and it is capable of creating a semi-permeable membrane in the skin. The invention also relates to a process for the manufacture of the skin preparation as defined above, which is characterized in that the lipophilic components are dissolved in water in a separate container to be combined with hydrophilic components, which have been blended and brought to react in another vessel. Finally, the present invention also relates to different uses of the skin preparation as defined above.
Inventor(s): Freij; Goran (Stockholm, SE)
Assignee: Ponsus AB (Stockholm, SE)
Application Number:09/008,632
Patent Claims: 1. A skin preparation comprising lipophilic and hydrophilic compounds suitable for application to the skin, which exists as a two-phase system which is capable of resulting in a semi-permeable membrane when applied to the skin, wherein said skin preparation is prepared by combination of about 5 to 8% by weight of a fatty acid comprising 14 to 20 carbon atoms, or a mixture of such fatty acids, about 0.73 to 2.66% of triethanolamine, about 4.5 to 7.0% of monopropylene glycol, about 1.5 to 1.97% of polyvinyl pyrrolidone, at most about 5.0% of dimethyl polysiloxane, and about 1 to 2% of at least one of glycerol, sorbitol, and polyethylene glycol, or a mixture thereof; and water, wherein the amount of water may comprise the balance of the preparation which totals 100%.

2. The skin preparation of claim 1, which is prepared by combination of 6.25% of at least one fatty acid comprising 14 to 20 carbon atoms as a mixture thereof, about 0.91% of triethanolamine, about 5.8% of monopropylene glycol, about 1.69% of polyvinyl pyrrolidone, about 0.5 to 0.95% of dimethyl polysiloxane, about 1.52% of at least one of glycerol, sorbitol, polyethylene glycol, or a mixture thereof, and water.

3. The skin preparation of claim 1, which further comprises a frothing agent.

4. The skin preparation of claim 3, wherein the amount of said frothing agent ranges from 1.3 to 3.7%.

5. The skin preparation of claim 4, wherein the amount of said frothing agent is about 1.5%.

6. The skin preparation of claim 1, which is in the form of a foam.

7. An aerosolic container which comprises the foam formulation of claim 6.

8. A method for preparing the skin preparation of claim 1, which comprises the following steps:

(a) dissolving and agitating in water at least one fatty acid comprising 14 to 20 carbon atoms or a mixture thereof in a vessel to produce solution A;

(b) dissolving and vigorously agitating in another vessel, water and polyvinyl pyrrolidone;

(c) adding to the vessel in step (b), during agitation, at least one of glycerol, sorbitol, polyethylene glycol, or mixture thereof, to produce solution B after a reaction time (t.sub.c);

(d) adding said solution B to said vessel comprising solution A and allowing a reaction to occur during a reaction time (t.sub.d); and

(e) cooling the product that results from step (d) by the addition of cold water and, while agitating, adding dimethyl polysiloxane thereto to produce said skin preparation.

9. The method of claim 8, wherein at least one of step (a) and step (b) is effected at a temperature of at least about 80.degree. C.

10. The method of claim 9, wherein at least one of step (a) and step (b) is effected at a temperature at least about 95.degree. C.

11. The method of claim 8, wherein t.sub.c is about 30 minutes, and t.sub.d is about 60 minutes.

12. A method for or alleviating itching or skin irritation comprising topically applying to a subject in need of such treatment a skin preparation according to claim 1.

13. The method of claim 12, which is used to treat contact dermatitis or eczema.

14. The method of claim 12, wherein said skin preparation is topically applied in conjunction with at least one active substance.

15. The method of claim 14, wherein said active substance is a therapeutic or veterinary agent.

16. The method of claim 14, wherein said active substance is a light absorbing or filtering agent.

17. A method of alleviating infection of the skin comprising topically applying to an area in need of such treatment a skin preparation according to claim 1.

18. A method of alleviating allergic reaction to metal comprising topically applying an effective amount of a skin preparation according to claim 1 a subject in need of such treatment.

19. The method of claim 12, wherein said skin preparation is topically applied in conjunction with at least one active agent selected from the group consisting of a sunscreen, sun-filtering agent, anaesthetic, fungicidal agent, and bactericide.

20. The method of claim 12, wherein said skin preparation is topically applied repeatedly to a subject in need of such topical application.
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