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BioPharmaceutical Business Intelligence

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Serving leading biopharmaceutical companies globally:

Covington
Johnson and Johnson
AstraZeneca
Deloitte
Argus Health
US Army
Teva
McKinsey
Daiichi Sankyo
US Department of Justice

Generated: November 17, 2017

DrugPatentWatch Database Preview

Claims for Patent: 5,900,423

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Claims for Patent: 5,900,423

Title: Form of paroxetine hydrochloride anhydrate
Abstract:"Paroxetine hydrochloride (I) anhydrate ##STR1## free of bound propan-2-ol, and various forms thereof, are useful in the treatment of depression and other disorders for which administration of selective serotonin reuptake inhibitors are indicated."
Inventor(s): Ward; Neal (Crowborough, GB), Jacewicz; Victor Witold (Tunbridge Wells, GB)
Assignee: SmithKline Beecham Corporation (Philadelphia, PA)
Application Number:08/922,060
Patent Claims: 1. Paroxetine hydrochloride anhydrate in Form A, which form comprises the following characteristics: a melting point of about 123-125.degree. C.; IR bands at about 513, 538, 571, 592, 613, 665, 722, 761, 783, 806, 818, 839, 888, 906, 924, 947, 966, 982, 1006, 1034, 1068, 1091, 1134, 1194, 1221, 1248, 1286, 1340, 1387, 1493, 1513, 1562, 1604, 3402, and 3631 cm.sup.-1 ; maximum endotherm, measured at 10.degree. C. per minute, of about 126.degree. C. in an open pan and about 121.degree. C. in a closed pan; characteristic X-ray diffractogram peaks at about 6.6, 8.0, 11.2, and 13.1 degrees 2 theta; characteristic solid state .sup.13 C-NMR spectrum peaks at about 154.3, 149.3, 141.6, and 138.5 ppm.
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Serving leading biopharmaceutical companies globally:

Queensland Health
Mallinckrodt
Accenture
QuintilesIMS
Boehringer Ingelheim
Argus Health
Medtronic
Colorcon
Harvard Business School
Farmers Insurance

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