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Claims for Patent: 5,866,581

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Claims for Patent: 5,866,581

Title: Penciclovir for the treatment of post therapeutic neuralgia
Abstract:A method for the treatment of PHN in mammals, including humans, which method comprises administering an effective amount of a compound of formula (A), or a pharmaceutically acceptable salt thereof. ##STR1##
Inventor(s): Boon; Ronald James (Dorking, GB2), Griffin; David Ronald John (Bishop's Stortford, GB2)
Assignee: SmithKline Beecham p.l.c. (Brentford, GB2)
Application Number:08/624,466
Patent Claims: 1. A method for the treatment of PHN in mammals, which method comprises administrating to the mammal in need of such treatment, an effective amount of famciclovir or penciclovir, or a pharmaceutically acceptable salt thereof.

2. A method according to claim 1 wherein the treatment is within 72 hours of rash onset.

3. A method according to claim 2 wherein the treatment is within 48 hours of rash onset.

4. A method according to claim 1 where the treatment period is 7 days.

5. A method according to claim 1 wherein the treatment is carried out on patients of greater than 50 years of age.

6. A method according to claim 5 wherein the treatment is carried out on patients of greater than 60 years of age.

7. A method according to claim 6 wherein the treatment is carried out on patients of greater than 70 years of age.

8. A method according to claim 1 wherein the compound is famciclovir.

9. A method according to claim 8 wherein famciclovir is administered at a dose of 250 mg, 500 mg or 750 mg, once, twice or three times a day.

10. A method according to claim 9 wherein famciclovir is administered at a dose of 250 mg three times a day.

11. A method according to claim 9 wherein famciclovir is administered at a dose of 500 mg three times a day.

12. A method according to claim 9 wherein famciclovir is administered at a dose of 500 mg twice a day.

13. A method according to claim 9 wherein famciclovir is administered at a dose of 750 mg once a day.

14. A method according to claim 1 wherein the mammal is a human.

15. A method for the prophylactic treatment of PHN in a human in need of such treatment, which method comprises administrating to said human, an effective prophylactic amount of famciclovir or penciclovir, or a pharmaceutically acceptable salt thereof.

16. A method according to claim 15 wherein the compound is famciclovir.

17. A method according to claim 16 wherein famciclovir is administered at a dose of 250 mg, 500 mg or 750 mg, once, twice or three times a day.

18. A method according to claim 17 wherein famciclovir is administered at a dose of 250 mg three times a day.

19. A method according to claim 15 wherein the treatment is carried out on patients of greater than 50 years of age.

20. A method according to claim 19 wherein the treatment is carried out on patients of greater than 60 years of age.

21. A method according to claim 20 wherein the treatment is carried out on patients of greater than 70 years of age.
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