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Generated: June 23, 2017

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Claims for Patent: 5,854,259

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Claims for Patent: 5,854,259

Title: Quinoline type mevalonolactones
Abstract:Described herein are mevalonolactone derivatives having a quinoline ring of formula (I) ##STR1## wherein the R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, Y and Z variables are described therein.
Inventor(s): Fujikawa; Yoshihiro (Funabashi, JP), Suzuki; Mikio (Funabashi, JP), Iwasaki; Hiroshi (Funabashi, JP), Sakashita; Mitsuaki (Saitama-ken, JP), Kitahara; Masaki (Saitama-ken, JP)
Assignee: Nissan Chemical Industries Ltd. (Tokyo, JP)
Application Number:07/978,884
Patent Claims: 1. A pharmaceutical composition for the control or treatment of at least one of hyperlipidemia, hyperlipoproteinemia, and atherosclerosis, comprising an active agent which consists of a compound of the formula, ##STR16## Z=--CH(OH)--CH.sub.2 --CH(OH)--CH.sub.2 --COO. 1/2Ca in a pharmaceutically effective amount together with a pharmacologically acceptable carrier.

2. The composition of claim 1 wherein said agent is an anti-hyperlipidemia agent.

3. The composition of claim 1, wherein said agent is an anti-hyperlipoproteinemia agent.

4. The composition of claim 1, wherein said agent is an anti-atherosclerosis agent.
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Serving 500+ biopharmaceutical companies globally:

Fish and Richardson
Moodys
Boehringer Ingelheim
Citi
Colorcon
Fuji
US Army
Healthtrust
Accenture
Mallinckrodt

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