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Claims for Patent: 5,840,757

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Claims for Patent: 5,840,757

Title: Lipid emulsion intended for parenteral or enteral feeding
Abstract:A lipid emulsion suitable for use as a parenteral or enteral foodstuff, wherein the lipid phase is a mixture of long-chain fatty acids in which 15 to 45% of the total fatty acids are essential fatty acids.
Inventor(s): Dutot; Guy (Noisy le Roi, FR)
Assignee: Clintec Nutrition Company (Deerfield, IL)
Application Number:07/755,610
Patent Claims: 1. A lipid emulsion suitable for use as a parenteral or enteral foodstuff, comprising from 5 to 50% by weight, relative to the total weight of the emulsion, of a lipid phase in water, said lipid phase consisting essentially of a mixture of long-chain fatty acids in which 15 to 45% by weight of the total fatty acids are essential fatty acids, the essential fatty acids being linoleic acid and .alpha.-linolenic acid.

2. A lipid emulsion according to claim 1 wherein the lipid phase comprises a mixture of two or more oils selected from the group consisting of apricot, almond, groundnut, avocado, wheat, safflower, rapeseed, coconut, cottonseed, lupin, maize, hazelnut, walnut, olive, oenothera, palm, palm-kernel, peach, grape, rice, rye, sesame, soybean, sunflower, tomato, linseed and citrus oils.

3. A lipid emulsion according to claim 2 wherein the lipid phase comprises, by weight, about 46% avocado oil and about 54% soybean oil.

4. A lipid emulsion according to claim 2 wherein the lipid phase comprises, by weight, about 47% olive oil and about 53% soybean oil.

5. A lipid emulsion according to claim 2 wherein the lipid phase comprises, by weight, about 60% avocado oil and about 40% walnut oil.

6. A lipid emulsion according to claim 2 wherein the lipid phase comprises, by weight, about 89% avocado oil and about 11% walnut oil.

7. A lipid emulsion according to claim 2 wherein the lipid phase comprises, by weight, about 11% walnut oil and about 89% olive oil.

8. A lipid emulsion according to claim 2 wherein the lipid phase comprises, by weight, about 85% olive oil and about 15% soybean oil.

9. A lipid emulsion according to claim 2 wherein the lipid phase comprises, by weight, about 40% walnut oil and about 60% olive oil.

10. A lipid emulsion according to claim 1 which further comprises, as an emulsifying agent, from 0.5 to 5% by weight, relative to the total weight of the emulsion, of plant, animal or synthetic phospholipids.

11. A lipid emulsion according to claim 1 which further comprises a tonicity-regulating agent.

12. A lipid emulsion according to claim 11 wherein the tonicity-regulating agent is selected from the group consisting of glycerol, glucose, a polyol and an amino acid.

13. An emulsion or solution comprising a lipid emulsion as defined in claim 1 and a solvent or adjuvant.

14. An emulsion or solution according to claim 13 wherein the emulsion or solution contains a pharmaceutically active ingredient.

15. An emulsion or solution according to claim 13 wherein the emulsion or solution is a dietetic composition.

16. A lipid emulsion suitable for use as a parenteral or enteral foodstuff, comprising from 5 to 50% by weight, relative to the total weight of the emulsion, of a lipid phase that comprises a mixture of at least two oils in water, said lipid phase consisting essentially of a mixture of long-chain fatty acids in which 15 to 45% by weight of the total fatty acids are essential fatty acids, the essential fatty acids being linoleic acid and .alpha.-linolenic acid.
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