Pharmaceutical Business Intelligence

  • Predict branded drug patent expiration
  • Uncover prior art in abandoned patent applications and expired patents
  • Drug patents and clinical trials in dozens of countries

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

How our clients use DrugPatentWatch

DrugPatentWatch Database Preview

Claims for Patent: 5,821,236

« Back to Dashboard

Claims for Patent: 5,821,236

Title: Tumor treatment with arabinofuranosyl purine derivatives
Abstract:6-Alkoxy derivatives of Ara-G, and pharmaceutically acceptable esters thereof, are described as being useful in tumor therapy. Novel pharmaceutically acceptable esters, their preparation and pharmaceutical formulations containing them are also disclosed.
Inventor(s): Krenitsky; Thomas Anthony (Chapel Hill, NC), Averett; Devron Randolph (Raleigh, NC), Koszalka; George Walter (Chapel Hill, NC)
Assignee: Glaxo Wellcome Inc. (Research Triangle Park, NC)
Application Number:08/449,078
Patent Claims: 1. A method for the inhibition of susceptible tumours in a mammal which comprises administering to said mammal an effective tumour inhibiting amount of a compound of the formula (I) ##STR2## wherein R.sup.1 is a C.sub.1-5 alkoxy group or a pharmaceutically acceptable ester or salt thereof.

2. A method according to claim 1 wherein R.sup.1 is methoxy.

3. The method of claim 1, wherein said compound is selected from the group consisting of




9-(2,3,5-tri-O-Acetyl-.beta.-D-arabinofuranosyl)-2-amino-6-methoxy-9H-purin e,


9-(2,3-di-O-Acetyl-.beta.-D-arabinofuranosyl)-2-amino-6-methoxy-9H-purine, and


or a pharmaceutically acceptable salt thereof.

4. The method of claim 1, wherein said compound is 2-amino-6-methoxy-9-(5-O-acetyl-.beta.-D-arabinofuranosyl)-9H-purine.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

How our clients use DrugPatentWatch

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.