Claims for Patent: 5,798,092
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Summary for Patent: 5,798,092
| Title: | Derivatized DTPA complexes pharmaceutical agents containing these compounds, their use, and processes for their production |
| Abstract: | Compounds of general Formula I ##STR1## wherein Z1 and Z2 in each case independently mean the residue --(CH.sub.2).sub.m --(C.sub.6 H.sub.4).sub.q --(O).sub.k --(CH.sub.2).sub.n --(C6 H4)l --(O)r --R, wherein m and n means the numbers 0-20, k, l, q and r means the numbers 0 and 1, and R means a hydrogen atom, an optionally OR1 -substituted C1 -C6 -alkyl residue, or a CH2 COOR1 group with R1 meaning a hydrogen atom, a C1 -C6 -alkyl residue, or a benzyl group, with the proviso that at least two substituents X stand for a metal ion equivalent; that one of the substituents Z1 and Z2 stands for a hydrogen and the other is not H; that--if n and l each means the number 0--k and r do not simultaneously mean the number 1; that --(O)r --R is not --OH; and that Z1 and Z2 are not --CH2 --C6 H4 --O--CH2 --COOCH2 C6 H5 or --CH2 --C6 H4 --O--(CH2)5 --COOCH2 C6 H5, are valuable pharmaceutical agents, e.g., for NMR or X-ray imaging. |
| Inventor(s): | Heribert Schmitt-Willich, Johannes Platzek, Heinz Gries, Gabrielle Schumann-Giampieri, Hanns-Joachim Weinmann, Hubert Vogler, Julius Deutsch, Juergen Conrad |
| Assignee: | Bayer Intellectual Property GmbH |
| Application Number: | US08/461,746 |
| Patent Claims: |
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