Claims for Patent: 5,795,864

Summary for Patent: 5,795,864

Title:	Stable omega conopetide formulations
Abstract:	Disclosed are formulations effective to stabilize omega conotoxin peptide preparations at elevated temperatures. Novel omega conopeptides also form part of the invention.
Inventor(s):	Amstutz; Gary Arthur (San Jose, CA), Bowersox; Stephen Scott (Menlo Park, CA), Gohil; Kishorchandra (Richmond, CA), Adriaenssens; Peter Isadore (Mountain View, CA), Kristipati; Ramasharma (Fremont, CA)
Assignee:	Neurex Corporation (Menlo Park, CA)
Application Number:	08/496,847
Patent Claims:	1. A stable omega conopeptide formulation comprising an omega conopeptide and an anti-oxidant composition capable of preventing methionine oxidation. 2. The formulation of claim 1, wherein the anti-oxidant composition includes a carboxylic acid buffer. 3. The formulation of claim 2, wherein the carboxylic acid buffer is lactate buffer. 4. The formulation of claim 1, wherein the anti-oxidant is methionine. 5. The formulation of claim 1, wherein the anti-oxidant composition includes lactate buffer and methionine. 6. An omega-conopeptide SNX-273 having the sequence: SEQ ID NO: 35. 7. An omega conopeptide SNX-279 having the sequence SEQ ID NO: 36.