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Generated: May 21, 2018

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Claims for Patent: 5,773,443

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Summary for Patent: 5,773,443
Title: Triazole antifungal agents
Abstract:The invention provides antifungal compounds of the formula: ##STR1## and pharmaceutically acceptable salts thereof, whereinR is phenyl substituted by 1 to 3 substituents each independently selected from halo, --CF.sub.3 and --OCF.sub.3 ; R.sup.1 is C.sub.1 -C.sub.4 alkyl; R.sup.2 is H or C.sub.1 -C.sub.4 alkyl; X is CH or N; and Y is F or Cl.
Inventor(s): Ray; Stephen J. (Groton, CT), Richardson; Kenneth (Groton, CT)
Assignee: Pfizer Inc. (New York, NY)
Application Number:08/683,694
Patent Claims: 1. A compound of the formula ##STR48## or a pharmaceutically acceptable salt thereof, wherein: R is phenyl substituted by two fluoro substituents.

2. A pharmaceutical composition for treating a fungal infection in a mammal which comprises an effective amount of the compound of claim 1 and a pharmaceutically acceptable carrier.

3. A method of treating a fungal infection in a mammal which comprises administering to said mammal an effective amount of the compound of claim 2.

4. The method of claim 3 wherein said fungal infection is caused by Aspergillus spp. fungi.

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Serving hundreds of leading biopharmaceutical companies globally:

Harvard Business School
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Daiichi Sankyo
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US Army

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