Generated: April 28, 2017
|Title:||Triazole antifungal agents|
|Abstract:||The invention provides antifungal compounds of the formula: ##STR1## and pharmaceutically acceptable salts thereof, whereinR is phenyl substituted by 1 to 3 substituents each independently selected from halo, --CF.sub.3 and --OCF.sub.3 ; R.sup.1 is C.sub.1 -C.sub.4 alkyl; R.sup.2 is H or C.sub.1 -C.sub.4 alkyl; X is CH or N; and Y is F or Cl.|
|Inventor(s):||Ray; Stephen J. (Groton, CT), Richardson; Kenneth (Groton, CT)|
|Assignee:||Pfizer Inc. (New York, NY)|
1. A compound of the formula ##STR48## or a pharmaceutically acceptable salt thereof, wherein: R is phenyl substituted by two fluoro substituents.
2. A pharmaceutical composition for treating a fungal infection in a mammal which comprises an effective amount of the compound of claim 1 and a pharmaceutically acceptable carrier.
3. A method of treating a fungal infection in a mammal which comprises administering to said mammal an effective amount of the compound of claim 2.
4. The method of claim 3 wherein said fungal infection is caused by Aspergillus spp. fungi.
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