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|Title:||Medicinal aerosol formulations|
|Abstract:||A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.|
|Inventor(s):||Purewal; Tarlochan S. (Leamington Spa, GB2), Greenleaf; David J. (Loughborough, GB2)|
|Assignee:||Riker Laboratories, Inc. (St. Paul, MN)|
1. In the method of delivering an aerosol formulation containing a medicament from an aerosol container equipped with a metering valve, said formulation being suitable for delivery to
the lung by inhalation from said container, the improvement comprising using in said formulation a propellant essentially free of chlorofluorocarbons and comprising 1,1,1,2-tetrafluoroethane.
2. A method according to claim 1, wherein said improvement further comprises the use of a compound selected from the group consisting of ethyl alcohol, isopropyl alcohol, n-pentane, isopentane, neopentane, and isopropyl myristate.
3. A method according to claim 1, wherein said medicament is salbutamol, beclomethasone dipropionate, disodium cromoglycate, pirbuterol, isoprenaline, adrenaline, rimiterol, or ipratropium bromide.
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