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Claims for Patent: 5,695,743

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Claims for Patent: 5,695,743

Title: Medicinal aerosol formulations
Abstract:A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
Inventor(s): Purewal; Tarlochan S. (Leamington Spa, GB2), Greenleaf; David J. (Loughborough, GB2)
Assignee: Riker Laboratories, Inc. (St. Paul, MN)
Application Number:08/026,476
Patent Claims: 1. An aerosol formulation comprising:

(a) a therapeutically effective amount of a medicament; and

(b) a propellant substantially free of chlorofluorocarbons, said propellant comprising 1,1,1,2-tetrafluoroethane,

said formulation being suitable for delivery to the lung by inhalation.

2. The formulation of claim 1 wherein said medicament is a member selected from the group consisting of salbutamol, beclomethasone dipropionate, disodium cromoglycate, pirbuterol, isoprenaline, adrenaline, rimiterol, and ipratropium bromide.

3. The formulation of claim 1, further comprising (c) a surface active agent.

4. A method for delivering a drug to the lung of a mammal, comprising administering to said mammal an aerosol formulation according to claim 1 by inhalation.

5. A method for treating a mammal having a condition capable of treatment by inhalation, comprising administering to the lung of said mammal an aerosol formulation according to claim 1 by inhalation.
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