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Claims for Patent: 5,683,677

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Claims for Patent: 5,683,677

Title: Medicinal aerosol formulations
Abstract:A self-propelling aerosol formulation which may be free from CFC's which comprises a medicament, 1,1,1,2-tetrafluoroethane, a surface active agent and at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane.
Inventor(s): Purewal; Tarlochan S. (Leamington Spa, GB2), Greenleaf; David J. (Loughborough, GB2)
Assignee: Riker Laboratories, Inc. (St. Paul, MN)
Application Number:08/455,012
Patent Claims: 1. A medicinal aerosol formulation, comprising:

(a) a therapeutically effective amount of a medicament;

(b) a propellant substantially free of chlorofluorocarbons and comprising 1,1,1,2-tetrafluoroethane; and

(c) wherein the medicament is fully dissolved in the formulation, and said formulation is suitable for delivery by inhalation.

2. The medicinal aerosol formulation of claim 1, further including at least one compound having a higher polarity than 1,1,1,2-tetrafluoroethane, selected from the group consisting of ethyl alcohol, isopropyl alcohol, n-pentane, isopentane, neopentane, and isopropyl myristate.

3. The medicinal aerosol formulation of claim 2, wherein said compound is ethyl alcohol.
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