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Last Updated: December 12, 2025

Claims for Patent: 5,604,213

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Summary for Patent: 5,604,213

Title:	17-substituted steroids useful in cancer treatment
Abstract:	Compounds of the general formula (1) (I) wherein X represents the residue of the A, B and C rings of a steroid, R represents a hydrogen atom or an alkyl group of 1 to 4 carbon atoms, R14 represents a hydrogen atom and R15 represents a hydrogen atom or an alkyl or alkoxy group of 1-4 carbon atoms, or a hydroxy or alkylcarbonyloxy group of 2 to 5 carbon atoms or R14 and R15 together represent a double bond, and R16 represents a hydrogen atom or an alkyl group of 1 to 4 carbon atoms, in the form of the free bases or phannaceutically acceptable acid addition salts, are useful for treatment of androgen-dependent disorders, especially prostatic cancer, and also oestrogen-dependent disorders such as breast cancer.
Inventor(s):	Susan E. Barrie, Michael Jarman, Gerard A. Potter, Ian R. Hardcastle
Assignee:	BTG International Ltd
Application Number:	US08/315,882
Patent Claims:

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