Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving 500+ biopharmaceutical companies globally:

Baxter
Boehringer Ingelheim
Fuji
Dow
Novartis
Chinese Patent Office
Harvard Business School
Teva
Accenture
Queensland Health

Generated: August 17, 2017

DrugPatentWatch Database Preview

Claims for Patent: ► Subscribe

« Back to Dashboard

Claims for Patent: ► Subscribe

Title: Medicaments for the treatment of nausea and vomiting
Abstract:The invention relates to the use of compounds of the general formula (I) ##STR1## wherein R.sup.1 represents a hydrogen atom or a C.sub.1-10 alkyl, C.sub.3-7 cycloalkyl, C.sub.-7 cycloalkyl-(C.sub.1-4) alkyl, C.sub.3-6 alkenyl, C.sub.3-10 alkynyl, phenyl or phenyl-C.sub.1-3 alkyl group; and one of the groups represented by R.sup.2, R.sup.3 and R.sup.4 is a hydrogen atom or a C.sub.1-6 alkyl, C.sub.3-7 cycloalkynyl, C.sub.2-6 alkenyl or phenyl-C.sub.1-3 alkyl group and each of the other two groups, which may be the same or different, represents a hydrogen atom or a C.sub.1-6 alkyl group; and physiologically acceptable salts and solvates thereof, for the relief of nausea and vomiting.
Inventor(s): Tyers; Michael B. (Welwyn, GB2), Coates; Ian H. (Hertford, GB2), Humber; David C. (Ealing, GB2), Ewan; George B. (Chalfont St. Peter, GB2), Bell; James A. (Melbourn, GB2)
Assignee: Glaxo Group Limited (GB2)
Application Number:07/501,974
Patent Claims: 1. A method of treatment of nausea and vomiting which comprises administering to a human or animal subject in need thereof an effective amount for the treatment of nausea and vomiting of a compound of formula (Ia) ##STR4## wherein R.sup.1a represents a hydrogen atom or a methyl, ethyl, propyl, prop-2-yl, prop-2-enyl or cyclopentyl group; R.sup.3a represents a hydrogen atom; and either R.sup.2a represents a methyl, ethyl, propyl or prop-2-yl group and R.sup.4a represents a hydrogen atom or R.sup.2a represents a hydrogen atom and R.sup.4a represents a methyl or ethyl group or a physiologically acceptable salt or solvate thereof.

2. A method of treatment of nausea and vomiting induced by an anti-cancer drug which is cisplatin, which comprises administering to a human or animal subject in need thereof an effective amount for the treatment of nausea and vomiting of a compound of formula (Ia) ##STR5## wherein R.sup.1a represents a hydrogen atom or a methyl, ethyl, propyl, prop-2-yl, prop-2-enyl or cyclopentyl group; R.sup.3a represents a hydrogen atom; and either R.sup.2a represents a methyl, ethyl, propyl or prop-2-yl group and R.sup.4a represents a hydrogen atom or R.sup.2a represents a hydrogen atom and R.sup.4a represents a methyl or ethyl group or a physiologically acceptable salt or solvate thereof.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

Serving 500+ biopharmaceutical companies globally:

Novartis
Covington
AstraZeneca
Colorcon
McKinsey
Cipla
Baxter
US Army
Deloitte
Chubb

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

Copyright 2002-2017 thinkBiotech LLC
ISSN: 2162-2639

Secure SSL Encrypted Heap | Mobile and Web Analytics
Privacy and Cookies
Terms & Conditions

Follow DrugPatentWatch:



Google
Twitter
Google Plus
botpot