|Title:|| Methods of treating androgenic alopecia with finasteride [17.beta.-N-mono-substituted-carbamoyl-4-aza-5-.alpha.-androst-1-en-ones]|
|Abstract:||17.beta.-N-monosubstituted-carbamoyl-4-5.alpha.-androst-1-en-3-ones of the formula ##STR1## wherein R.sup.1 is selected from hydrogen, methyl and ethyl and R.sup.2 is a branched chain alkyl of from 3-12 carbons, and R', R", R'" are hydrogen or methyl are active as testosterone 5.alpha.-reductase inhibitors and thus are useful topically for treatment of androgenic alopecia.|
|Inventor(s):|| Rasmusson; Gary H. (Watchung, NJ), Reynolds; Glenn F. (Westfield, NJ) |
|Assignee:|| Merck & Co., Inc. (Rahway, NJ) |
1. A method of treating androgenic alopecia which comprises orally administering to a human in need of such treatment a therapeutically effective amount of
2. The method of claim 1 wherein the androgenic alopecia is male pattern alopecia.