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Claims for Patent: 5,571,817

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Claims for Patent: 5,571,817

Title: Methods of treating androgenic alopecia with finasteride [17.beta.-N-mono-substituted-carbamoyl-4-aza-5-.alpha.-androst-1-en-ones]
Abstract:17.beta.-N-monosubstituted-carbamoyl-4-5.alpha.-androst-1-en-3-ones of the formula ##STR1## wherein R.sup.1 is selected from hydrogen, methyl and ethyl and R.sup.2 is a branched chain alkyl of from 3-12 carbons, and R', R", R'" are hydrogen or methyl are active as testosterone 5.alpha.-reductase inhibitors and thus are useful topically for treatment of androgenic alopecia.
Inventor(s): Rasmusson; Gary H. (Watchung, NJ), Reynolds; Glenn F. (Westfield, NJ)
Assignee: Merck & Co., Inc. (Rahway, NJ)
Application Number:08/094,815
Patent Claims: 1. A method of treating androgenic alopecia which comprises orally administering to a human in need of such treatment a therapeutically effective amount of 17.beta.-(N-tert-butylcarbamoyl)-4-aza-5.alpha.-androst-1-en-3-one.

2. The method of claim 1 wherein the androgenic alopecia is male pattern alopecia.
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