Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving hundreds of leading biopharmaceutical companies globally:

Fish and Richardson
Citi
Argus Health
Farmers Insurance
Merck
Deloitte
QuintilesIMS
Moodys
Healthtrust

Generated: April 21, 2018

DrugPatentWatch Database Preview

Claims for Patent: 5,562,925

« Back to Dashboard

Summary for Patent: 5,562,925
Title: Anti-tumor method
Abstract:Malignant tumors in animals are treated by parenterally administering to an affected animal a solution containing a complex compound of platinum in an amount effective to cause regression of the tumor.
Inventor(s): Rosenberg; Barnett (Holt, MI), Vancamp; Loretta (East Lansing, MI), Krigas; Thomas (Okemos, MI)
Assignee: Research Corporation Tech. Inc. (Tucson, AZ)
Application Number:08/252,668
Patent Claims: 1. A therapeutic composition comprising a therapeutically effective amount of an inorganic planar dsp.sup.2 platinum (II) coordination complex, which complex is protected from light, and which is suitable for therapeutic administration by injection in solution therefor, wherein the donor ligands are Cl, Br, CN, NH.sub.3, OS, NO.sub.3, H.sub.2 O, hydroxy, ethylene diamine, or propylene diamine, and wherein the donor ligands of the complex form coordinate covalent bonds with the central platinum ion.

2. The therapeutic composition according to claim 1 wherein the platinum coordination complex is dissolved in a stabilizing effective amount of a saline or buffer solution.

3. The therapeutic composition according to claim 1 wherein the platinum complex is in the cis configuration.

4. The therapeutic composition according to claim 3 wherein the platinum complex is cis chloroplatinumamine.

5. The therapeutic composition according to claim 4 which is cis-Pt(II)(NH.sub.3).sub.2 Cl.sub.2.

6. The therapeutic composition according to claim 1 which is Pt(II)(NH.sub.2 CH.sub.2 CH.sub.2 NH.sub.2) Cl.sub.2.

For more information try a trial or see the plans and pricing

Serving hundreds of leading biopharmaceutical companies globally:

Farmers Insurance
Merck
Medtronic
McKinsey
Deloitte
Cerilliant
Colorcon
Teva
Argus Health

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.