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Serving leading biopharmaceutical companies globally:

UBS
McKesson
Medtronic
Dow
Harvard Business School
AstraZeneca
Teva
Federal Trade Commission
Fuji
Mallinckrodt

Generated: February 20, 2018

DrugPatentWatch Database Preview

Claims for Patent: 5,508,020

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Summary for Patent: 5,508,020
Title: Technetium-99M labeled peptides for imaging
Abstract:This invention relates to radiolabeled peptides and methods for producing such peptides. Specifically, the invention relates to peptides, methods and kits for making such peptides, and methods for using such peptides to image sites in a mammalian body labeled with technetium-99m (Tc-99m) via Tc-99m binding moieties. In particular, the peptide reagents of the invention are covalently linked to a polyvalent linker moiety, so that the polyvalent linker moiety is covalently linked to a multiplicity of the specific-binding peptides, and the Tc-99m binding moieties are covalently linked to a plurality of the specific-binding peptides, the polyvalent linker moiety, or to both the specific-binding peptides and the polyvalent linker moiety.
Inventor(s): Dean; Richard T. (Bedford, NH), Lister-James; John (Bedford, NH)
Assignee: Diatech, Inc. (Londonderry, NH)
Application Number:07/893,981
Patent Claims: 1. A composition of matter comprising a reagent for preparing a scintigraphic imaging agent for imaging sites within a mammalian body comprising a multiplicity of specific-binding peptides, each specific binding peptide having an amino acid sequence of 3 to 100 amino acids wherein the specific binding peptide specifically binds to a site in a mammalian body, covalently linked to a polyvalent linking moiety, and a technetium-99m binding moiety covalently linked to a plurality of the specific-binding peptides, the polyvalent linker moiety, or both, wherein the reagent is selected from the group consisting of reagents having the formula: ##STR8##

2. A composition of matter having the formula: ##STR9##

3. A composition of matter having the formula: ##STR10##

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Moodys
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AstraZeneca
Cipla
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Chinese Patent Office
US Department of Justice
Mallinckrodt

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