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Last Updated: December 15, 2025

Claims for Patent: 5,480,656

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Summary for Patent: 5,480,656

Title:	Prolonged release microcapsules
Abstract:	This invention provides a microcapsule designed for zero order release of a physiologically active polypeptide over a period of at least two months, which is produced by preparing a water-in-oil emulsion comprising an inner aqueous layer containing about 20 to 70% (w/w) of said polypeptide and an oil layer containing a copolymer or homopolymer having a weight-average molecular weight of 7,000 to 30,000, wherein the composition ratio of lactic acid/glycolic acid in the copolymer or homopolymer is 80/10 to 100/0, and then subjecting said water-in oil emulsion to microencapsulation.
Inventor(s):	Hiroaki Okada, Yayoi Inoue, Yasuaki Ogawa
Assignee:	Takeda Pharmaceutical Co Ltd
Application Number:	US08/188,918
Patent Claims:

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