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Claims for Patent: 5,459,163

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Claims for Patent: 5,459,163

Title: Medicament to combat autoimmune diseases
Abstract:A pharmaceutical composition for use in the treatment of chronic Graft-versus-host diseases as well as autoimmune diseases, in particular for the treatment of systemic lupus erythematosus containing as an active ingredient at least one compound of the formulae 1 or 2 ##STR1## the latter being present per se or in the form of a physiologically tolerable salt. The invention also relates to a dosage unit form of said pharmaceutical composition and a method of treating chronic Graft-versus host diseases as well as autoimmune diseases, in particular systemic lupus erythematosus.
Inventor(s): Bartlett; Robert R. (Darmstadt, DE), Schleyerbach; Rudolph (Hofheim am Taunus, DE), Kammerer; Friedrich-Johannes (Hochheim am Main, DE)
Assignee: Hoechst Aktiengesellschaft (Frankfurt, DE)
Application Number:08/119,840
Patent Claims: 1. A composition comprising N-(4-trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide having the formula: ##STR2## and a pharmaceutically acceptable carrier.
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