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|Title:||Medicament to combat autoimmune diseases|
|Abstract:||A pharmaceutical composition for use in the treatment of chronic Graft-versus-host diseases as well as autoimmune diseases, in particular for the treatment of systemic lupus erythematosus containing as an active ingredient at least one compound of the formulae 1 or 2 ##STR1## the latter being present per se or in the form of a physiologically tolerable salt. The invention also relates to a dosage unit form of said pharmaceutical composition and a method of treating chronic Graft-versus host diseases as well as autoimmune diseases, in particular systemic lupus erythematosus.|
|Inventor(s):||Bartlett; Robert R. (Darmstadt, DE), Schleyerbach; Rudolph (Hofheim am Taunus, DE), Kammerer; Friedrich-Johannes (Hochheim am Main, DE)|
|Assignee:||Hoechst Aktiengesellschaft (Frankfurt, DE)|
|Patent Claims:||1. A composition comprising N-(4-trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide having the formula: ##STR2## and a pharmaceutically acceptable carrier.|
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