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Serving hundreds of leading biopharmaceutical companies globally:

Healthtrust
Johnson and Johnson
AstraZeneca
Teva
Fish and Richardson
Julphar
Mallinckrodt
Cantor Fitzgerald
Cerilliant

Generated: April 22, 2018

DrugPatentWatch Database Preview

Claims for Patent: 5,455,044

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Summary for Patent: 5,455,044
Title: Method for treating neurological disorders
Abstract:A method for ameliorating a neurological disorder in a human by administration to the cerebrospinal fluid (CSF) of a therapeutic agent in a dispersion system which allows the therapeutic agent to persist in the cerebro-ventricular space.
Inventor(s): Kim; Sinil (Solana Beach, CA), Howell; Stephen B. (Del Mar, CA)
Assignee: DepoTech Corporation (LaJolla, CA)
Application Number:08/062,799
Patent Claims: 1. A method for ameliorating a cell proliferative disease which comprises intralumbar administration to the cerebrospinal fluid (CSF) of a human with the disease of a therapeutically effective amount of an antitumor drug in a synthetic membrane vesicle such that the antitumor agent persists in the cerebro-ventricular space for a time sufficient to ameliorate the disease.

2. The method of claim 1, wherein the synthetic membrane vesicle is a liposome.

3. The method of claim 2, wherein the liposome contains multiple concentric chambers.

4. The method of claim 1, wherein the synthetic membrane vesicle contains multiple non-concentric chambers.

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Serving hundreds of leading biopharmaceutical companies globally:

Harvard Business School
Argus Health
Moodys
US Department of Justice
AstraZeneca
Queensland Health
Daiichi Sankyo
Express Scripts
Farmers Insurance

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