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Last Updated: December 12, 2025

Claims for Patent: 5,438,071

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Summary for Patent: 5,438,071

Title:	Stable porfimer sodium compositions and methods for their manufacture
Abstract:	A storage stable porfimer sodium (polyhematoporphyrin ether/ester) composition useful in the photodynamic therapy of cancer and other conditions is provided. The composition is characterized in that the percentage of ester linked porphyrin oligomers is less than 10% of the composition. Improved processes for preparing such compositions are also provided wherein acetylated hematoporphyrin is treated with alkali for sufficient time and temperature to reduce the amount of porphyrin oligomers joined by ester linkages to less than 10% of the composition.
Inventor(s):	Steven L. Clauss, Michael J. Pastel, Rainer K. Zawadzki
Assignee:	Novelion Therapeutics Inc, Wyeth Holdings LLC, Pinnacle Biologics Inc
Application Number:	US08/075,227
Patent Claims:

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