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Serving leading biopharmaceutical companies globally:

Argus Health
Johnson and Johnson
Daiichi Sankyo
Fish and Richardson
Farmers Insurance

Generated: October 23, 2017

DrugPatentWatch Database Preview

Claims for Patent: 5,412,095

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Claims for Patent: 5,412,095

Title: Terazosin monohydrochloride and processes and intermediate for its production
Abstract:The present invention provides a non-solvated crystalline polymorph of terazosin monohydrochloride designated Form III and methods for its preparation. Also disclosed is terazosin monohydrochloride methanolate and processes for its production as well as processes for its conversion to other crystalline forms of terazosin monohydrochloride.
Inventor(s): Morley; James A. (Gurnee, IL), Bauer; John F. (Lake Bluff, IL), Patel; Ramesh F. (Chicago, IL), Henry; Rodger E. (Waukegan, IL), Spanton; Stephen G. (Grayslake, IL)
Assignee: Abbott Laboratories (Abbott Park, IL)
Application Number:08/246,526
Patent Claims: 1. The compound having the name 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-furoyl)piperazine monohydrochloride methanolate characterized by peaks in the powder x-ray diffraction pattern at values of two theta of 5.09.degree.35 0.2.degree.; 9.63.degree..+-.0.2.degree.; 11.64.degree..+-.0.2.degree.; 15.32.degree..+-.0.2.degree.; 16.63.degree..+-.0.2.degree.; 21.25.degree..+-.0.2.degree.; 22.24.degree..+-.0.2.degree.; 22.28.degree..+-.0.2.degree.; 26.62.degree..+-.0.2.degree.; and 28.93.degree..+-.0.2.degree..

2. The non-solvated crystalline polymorph of 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-furoyl)piperazine monohydrochloride characterized by peaks in the powder x-ray diffraction pattern at values of two theta of 7.29.degree..+-.0.2.degree.; 11.81.degree..+-.0.2.degree.; 14.59.degree..+-.0.2.degree.; 19.43.degree..+-.0.2.degree.; 20.40.degree..+-.0.2.degree.; 21.61.degree..+-.0.2.degree.; 22.36.degree..+-.0.2.degree.; 23.69.degree..+-.0.2.degree.; 24.34.degree..+-.0.2.degree.; 24.80.degree..+-.0.20.degree.; 25.75.degree..+-.0.2.degree.; 27.29.degree..+-.0.2.degree.; 29.96.degree..+-.0.2.degree.; and 31.20.degree..+-.0.2.degree..
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Serving leading biopharmaceutical companies globally:

Argus Health
Daiichi Sankyo
US Department of Justice
Fish and Richardson
Queensland Health
Boehringer Ingelheim

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