You're using a free limited version of DrugPatentWatch: Upgrade for Complete Access

Last Updated: October 4, 2024

Claims for Patent: 5,412,095


✉ Email this page to a colleague

« Back to Dashboard


Summary for Patent: 5,412,095
Title: Terazosin monohydrochloride and processes and intermediate for its production
Abstract:The present invention provides a non-solvated crystalline polymorph of terazosin monohydrochloride designated Form III and methods for its preparation. Also disclosed is terazosin monohydrochloride methanolate and processes for its production as well as processes for its conversion to other crystalline forms of terazosin monohydrochloride.
Inventor(s): Morley; James A. (Gurnee, IL), Bauer; John F. (Lake Bluff, IL), Patel; Ramesh F. (Chicago, IL), Henry; Rodger E. (Waukegan, IL), Spanton; Stephen G. (Grayslake, IL)
Assignee: Abbott Laboratories (Abbott Park, IL)
Application Number:08/246,526
Patent Claims: 1. The compound having the name 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-furoyl)piperazine monohydrochloride methanolate characterized by peaks in the powder x-ray diffraction pattern at values of two theta of 5.09.degree.35 0.2.degree.; 9.63.degree..+-.0.2.degree.; 11.64.degree..+-.0.2.degree.; 15.32.degree..+-.0.2.degree.; 16.63.degree..+-.0.2.degree.; 21.25.degree..+-.0.2.degree.; 22.24.degree..+-.0.2.degree.; 22.28.degree..+-.0.2.degree.; 26.62.degree..+-.0.2.degree.; and 28.93.degree..+-.0.2.degree..

2. The non-solvated crystalline polymorph of 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-furoyl)piperazine monohydrochloride characterized by peaks in the powder x-ray diffraction pattern at values of two theta of 7.29.degree..+-.0.2.degree.; 11.81.degree..+-.0.2.degree.; 14.59.degree..+-.0.2.degree.; 19.43.degree..+-.0.2.degree.; 20.40.degree..+-.0.2.degree.; 21.61.degree..+-.0.2.degree.; 22.36.degree..+-.0.2.degree.; 23.69.degree..+-.0.2.degree.; 24.34.degree..+-.0.2.degree.; 24.80.degree..+-.0.20.degree.; 25.75.degree..+-.0.2.degree.; 27.29.degree..+-.0.2.degree.; 29.96.degree..+-.0.2.degree.; and 31.20.degree..+-.0.2.degree..

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.