.

Pharmaceutical Business Intelligence

  • Anticipate P&T budget requirements
  • Evaluate market entry opportunities
  • Find generic sources and suppliers
  • Predict branded drug patent expiration

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

DrugPatentWatch Database Preview

Claims for Patent: 5,384,310

« Back to Dashboard

Claims for Patent: 5,384,310

Title: 2'-fluoro-2-haloarabinoadinosines and their pharmaceutical compositions
Abstract:The present invention is directed to certain 2'-fluoro, 2-substituted purine nucleosides which are toxic to cancerous cell lines.
Inventor(s): Montgomery; John A. (Birmingham, AL), Secrist, III; John A. (Birmingham, AL)
Assignee: Southern Research Institute (Birmingham, AL)
Application Number:07/693,646
Patent Claims: 1. A pharmaceutical composition comprising a compound of the formula ##STR6## wherein R, each which may be the same or different, is hydrogen or a protecting group; wherein Z is a halogen of the group F, Cl, and Br; and pharmaceutically acceptable salts thereof, said composition being in combination with a pharmaceutically acceptable carrier for oral, topical, or parenteral administration.

2. A pharmaceutical composition according to claim 1 wherein R is a protecting group.

3. A pharmaceutical composition according to claim 1 wherein R is hydrogen.

4. A pharmaceutical composition according to claims 1, 2 or 3 wherein Z is Cl.

5. A pharmaceutical composition according to claim 1 wherein the compound is 2-Chloro-9-(2-deoxy-2-fluoro-.beta.-D arabinofuranosyl)-9H-purin-6-amine.

6. A purine nucleoside having the formula ##STR7## wherein R, each which may be the same or different, is hydrogen or a protecting group; wherein Z is a halogen of the group F, Cl, and Br; and pharmaceutically acceptable salts thereof.

7. A purine nucleoside according to claim 6 wherein R is hydrogen.

8. A purine nucleoside according to claim 6 wherein R is a protecting group.

9. A purine nucleoside according to claims 6, 7 or 8 wherein Z is Cl.

10. A purine nucleoside according to claim 6 which is 2-Chloro-9-(2-deoxy-2-fluoro-.beta.-D arabinofuranosyl)-9H-purin-6-amine.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

`abc