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|Title:||5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection|
|Abstract:||Disclosed are novel 5,11-dihydro-6H-dipyrido[3,2-b; 2',3'-e][1,4]diazepines. These are useful in the prevention or treatment of HIV infection.|
|Inventor(s):||Hargrave; Karl D. (Brookfield, CT), Proudfoot; John R. (Newtown, CT), Adams; Julian (Ridgefield, CT), Grozinger; Karl G. (Ridgefield, CT), Schmidt, deceased; Gunther (late of Munich, DE), Engel; Wolfhard (Biberach, DE), Trummlitz; Gunther (Warthausen, DE), Eberlein; Wolfgang (Biberach, DE)|
|Assignee:||Boehringer Ingelheim Pharmaceuticals, Inc. (Ridgefield, CT)|
1. 11-Cyclopro pyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, or a pharmaceutically acceptable salt thereof.
2. A method for treating HIV-1 infection which comprises administering to a human being infected by HIV- 1 a therapeutically effective amount of 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazep in-6-one or a pharmaceutically acceptable salt thereof.
3. A pharmaceutical composition, suitable for treating HIV-1 infection, which comprises a therapeutically effective amount of 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazep in-6-one or a pharmaceutically acceptable salt thereof.
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