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Claims for Patent: 5,307,953

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Claims for Patent: 5,307,953

Title: Single dose dispenser having a piercing member
Abstract:The application describes a dispenser for manual discharge of a single dose of a flowable substance, comprising a casing (1) which has a nozzle (2) and a pair of shoulders (3) aside the nozzle. The nozzle (2) has a piston member (5) extending inwardly from an outlet opening (9), the piston member having at least one discharge channel. A container (10) of the substance to be discharged is mounted on the piston member (5), and a seal (12) is arranged across the container (10) to seal in all the substances to be discharged. The piston member (5) has a piercing member (8) which extends towards the seal (12), whereby on pressing the container (10) on to the piston member (5) the seal (12) is pierced to allow the contents of the container (10) to be expelled along the discharge channel and out through the outlet opening (9).
Inventor(s): Regan; Philip M. (Ware, GB3)
Assignee: Glaxo Group Limited (Middlesex, GB)
Application Number:07/984,913
Patent Claims: 1. A unit-dose dispenser for manual discharge of a single dose of a flowable substance in the form of a spray, comprising a casing which has a nozzle and two shoulders, one on either side of this nozzle, the nozzle having a piston member extending inwardly from and outlet opening, the piston member having at least one discharge channel, a container of the substance to be discharged being operatively positioned with respect to the piston member, and a seal being arranged across the container to seal in all the substance to be discharged, the piston member having a piercing member which extends towards the seal, whereby on pressing the container onto the piston member the seal is pierced to allow the contents of the container to be expelled along the discharge channel and out through the outlet opening in the form of the spray.

2. A dispenser according to claim 1, wherein the seal is formed by a stopper which is movably engaged inside the container and has a central membrane which, in use, is pierced by the piercing member.

3. A dispenser according to claim 2, wherein the piercing member is hollow, thereby forming the discharge channel of the piston.

4. A dispenser according to claim 3, wherein the piercing member extends along the axis of the piston member to the outlet opening.

5. A dispenser according to claim 4, wherein the piercing member is a steel needle.

6. A dispenser according to claim 1, wherein the container engages on the inside of the casing, the engagement being released by a predetermined force which provides for efficient discharge of the substance in the container.

7. A dispenser according to claim 1, wherein the container contains a pharmaceutical substance.

8. A dispenser according to claim 7, wherein the substance is for the treatment of migraine, influenza, respiratory diseases or allergic rhinitis.

9. A dispenser according to claim 7, wherein the pharmaceutical substance is sumatriptan.

10. A dispenser according to claim 7, wherein the discharge volume of the substance is substantially 0.1 ml.

11. A unit-dose dispenser for manual discharge of a single dose of a flowable substance in the form of a spray, comprising a casing which contains a nozzle and two shoulders, one on either side of the nozzle, the nozzle incorporating a piston member extending inwardly from an outlet opening, the piston member having at least one discharge channel, and a container of the substance to be discharged being operatively positioned with respect to the piston member and within the casing, wherein a seal is arranged across the container to seal in all the substance to be discharged, and wherein the piston member has a piercing member which extends towards the seal, whereby on pressing the container onto the piston member the seal is pierced to allow the contents of the container to be expelled along the discharge channel and out through the outlet opening in the form of a spray.

12. A dispenser according to claim 11, wherein the seal is formed by a stopper which is movably engaged inside the container and has a central membrane which, in use, is pierced by the piercing member.

13. A dispenser according to claim 12, wherein the piercing member is hollow, thereby forming the discharge channel of the piston.

14. A dispenser according to claim 13, wherein the piercing member extends along the axis of the piston member to the outlet opening.

15. A dispenser according to claim 14, wherein the piercing member is a steel needle.

16. A dispenser according to claim 11, wherein the container engages on the inside of the casing, the engagement being released by a predetermined force which provides for efficient discharge of the substance in the container.

17. A dispenser according to claim 11, wherein the container contains a pharmaceutical substance.

18. A dispenser according to claim 17, wherein the substance is for the treatment of one of migraine, influenza, respiratory disease and allergic rhinitis.

19. A dispenser according to claim 17, wherein the pharmaceutical substance is sumatriptan.

20. A dispenser according to claim 17, wherein the discharge volume of the substance is substantially 0.1 ml.
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