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Last Updated: December 12, 2025

Claims for Patent: 5,202,128

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Summary for Patent: 5,202,128

Title:	Sustained release pharmaceutical composition
Abstract:	The present invention relates to a pharmaceutical pellet composition having a core element including at least one highly soluble active ingredient and a core coating which is partially soluble at a highly acidic pH. The pharmaceutical composition provides a slow release of active ingredient at a highly acidic pH and provides a constant, relatively faster rate of release at a more alkaline pH such as that of the intestine. Oral administration of the pharmaceutical pellet composition of the present invention to a patient is effective to deliver to the blood levels of active ingredient within the therapeutic range and to maintain such levels over an extended period of time.
Inventor(s):	Angelo M. Morella, Mark C. Fisher
Assignee:	Alpharma Pharmaceuticals LLC
Application Number:	US07/574,551
Patent Claims:

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