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Serving hundreds of leading biopharmaceutical companies globally:

Harvard Business School
Boehringer Ingelheim
Healthtrust
Medtronic
Fuji
Fish and Richardson
Chubb
Julphar
Argus Health

Generated: May 21, 2018

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Claims for Patent: 5,180,715

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Summary for Patent: 5,180,715
Title: Irrigation of internal bladder surfaces in mammals with sodium pentosanpolysulfate
Abstract:The method of treating bladder infections, interstitial cystitis and tumors in mammals which comprises the irrigation of the internal bladder and associated surfaces with an irrigating solution containing an effective amount of sodium pentosanpolysulfate. Also, the treatment of interstitial cystitis by the oral administration of sodium pentosanpolysulfate at high dosages on the order of 200 mg. per day or more.
Inventor(s): Parsons; C. Lowell (San Diego, CA)
Assignee: The Regents of the University of California (Oakland, CA)
Application Number:07/387,402
Patent Claims: 1. A method of treating bladder infections in mammals which comprises irrigating the internal bladder and associated surfaces with an irrigating solution containing an effective amount of sodium pentosanpolysulfate.

2. The method of claim 1 wherein the irrigating solution is saline.

3. The method of claim 1 wherein sodium pentosanpolysulfate is present in the irrigating solution in an amount of from about 1 to 20 mg/ml.

4. The method of claim 1 wherein sodium pentosanpolysulfate is present in the irrigating solution in an amount of from about 5 to 20 mg/ml.

5. A method of treating interstitial cystitis in mammals which comprises irrigating the internal bladder and associated surfaces with an irrigating solution containing an effective amount of sodium pentosanpolysulfate.

6. The method of claim 5 wherein the irrigating solution is saline.

7. The method of claim 5 wherein sodium pentosanpolysulfate is present in the irrigating solution in an amount of from about 1 to 20 mg/ml.

8. The method of claim 5 wherein sodium pentosanpolysulfate is present in the irrigating solution in an amount of from about 5 to 20 mg/ml.

9. A method of treating interstitial cystitis in a mammal which comprises orally administering an effective amount of sodium pentosanpolysulfate to the mammal in need of such treatment.

10. The method of claim 9 wherein at least about 100 mg of sodium pentosanpolysulfate is administered per day.

11. The method of claim 9 wherein about 150 to 300 mg of sodium pentosanpolysulfate is administered per day.

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Serving hundreds of leading biopharmaceutical companies globally:

US Army
McKinsey
US Department of Justice
Federal Trade Commission
Colorcon
Daiichi Sankyo
Mallinckrodt
UBS
Harvard Business School

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