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Generated: June 21, 2018

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Claims for Patent: 5,155,268

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Summary for Patent: 5,155,268
Title: Antiarrhythmic N-aminoalkylene alkyl and aryl sulfonamides
Abstract:The present invention provides novel sulfonanilide and benzene-alkylaminium compounds which are the products of processes utilizing novel intermediates. Both the novel compounds and the novel intermediates are useful for the therapeutic or prophylactic treatment of arrhythmic activity.
Inventor(s): Hester, Jr.; Jackson B. (Galesburg, MI)
Assignee: The Upjohn Company (Kalamazoo, MI)
Application Number:07/423,499
Patent Claims: 1. The compound selected from the group consisting of: (a) N,N-diethyl-N-heptyl-.beta.-hydroxy-4-[(methylsulfonyl)amino]benzeneethana minium bromide;

(b) N,N-diethyl-N-heptyl-.delta.-hydroxy-4-[(methylsulfonyl)amino]benzenebutan aminium bromide; and,

(c) N,N-diethyl-N-heptyl-.gamma.-hydroxy-4-[(methylsulfonyl)amino]benzenepropa naminium bromide.

2. A hydroxy-alkylene compound and pharmaceutically acceptable salts thereof which is

(a) N-(4-(4-(ethylheptylamino)-1-hydroxybutyl)phenyl)methanesulfonamide; or

(b) N-(4-(4-dibutylamino)-1-hydroxybutyl)phenyl)methanesulfonamide.

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