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Drug patents …
… from Kazakhstan to Kalamazoo
|Title:||Dibenz[b,e]oxepin derivative and pharmaceutical compositions thereof|
|Abstract:||Novel dibenz[b,e]oxepin derivatives are employed in the treatment and control of allergic conditions such as allergic asthma and also employed in the treatment of inflammation.|
|Inventor(s):||Oshima; Etsuo (Shizuoka, JP), Kumazawa; Toshiaki (Shizuoka, JP), Otaki; Shizuo (Shizuoka, JP), Obase; Hiroyuki (Shizuoka, JP), Ohmori; Kenji (Mishima, JP), Ishii; Hidee (Shizuoka, JP), Manabe; Haruhiko (Shizuoka, JP), Tamura; Tadafumi (Shizuoka, JP), Shuto; Katsuichi (Shizuoka, JP)|
|Assignee:||Kyowa Hakko Kogyo Co., Ltd. (Tokyo, JP)|
1. A dibenz[b,e]oxepin compound in cis form having the formula ##STR55## and pharmaceutically acceptable salts thereof.
2. A compound according to claim 1, wherein said salt is selected from the group consisting of acid addition salt, metal salt, ammonium salt, organic amine addition salt, and amino acid addition salt.
3. A pharmaceutical composition comprising a pharmaceutical carrier and as an active ingredient, an effective amount of a dibenz[b,e]oxepin compound defined in claim 1.