Claims for Patent: 5,089,509

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Summary for Patent: 5,089,509

Title:	Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity
Abstract:	Retinoid-like activity is exhibited by compounds of the formula ##STR1## where X is S, O, or NR' where R' is hydrogen or lower alkyl; R is hydrogen or lower alkyl; A is pyridyl, thienyl, furyl, pyridazinyl, pyrimidinyl or pyrazinyl; n is 0-2; and B is H, --COOH or a pharmaceutically acceptable salt, ester or amide thereof, --CH2 OH or an ether or ester derivative, or --CHO or an acetal derivative, or --COR1 or a ketal derivative where R1 is --(CH2)m CH3 where m is 0-4, or a pharmaceutically acceptable salt thereof.
Inventor(s):	Roshantha A. S. Chandraratna
Assignee:	Allergan Inc
Application Number:	US07/326,191
Patent Claims:

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