Flexible Flat-Rate Plans

Flat-rate pricing for predictable budgeting

Short-term plans for project- or client-based billing

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

DrugPatentWatch Database Preview

Claims for Patent: 5,087,454

« Back to Dashboard

Claims for Patent: 5,087,454

Title: Ibuprofen tablet
Abstract:Ibuprofen tablets/caplets formed by wet granulation of the ibuprofen characterized by a dissolution profile maintained stable on aging by incorporating croscarmellose sodium separately into the wet granulation and the compression mix and further incorporating sodium lauryl sulfate into the compression mix.
Inventor(s): Duerholz; Joanne R. (Medford, NJ), DiMaria; Dolores (Vineland, NJ), Blank; Robert G. (Hammonton, NJ)
Assignee: American Home Products Corporation (New York, NY)
Application Number:07/559,862
Patent Claims: 1. In an ibuprofen compressed tablet/caplet containing about 50% to about 70% by weight based on the weight of the tablet/caplet core of ibuprofen formed by (a) wet granulating the ibuprofen with an excipient comprising starch to provide a dry base granulation (b) formulating a compression mix containing the dry base granulation and an excipient comprising starch, and (c) tabletting the compression mix, the improvement which comprises providing a compressed tablet having an improved dissolution profile maintained stable on aging by (1) separately incorporating into each of the wet granulation and the compression mix about 1% to about 2% by weight based on the weight of the compressed tablet core of croscarmellose sodium and (2) incorporating into the compression mix about 0.05 to about 0.15% by weight of the compressed tablet core of sodium lauryl sulfate.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.