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|Title:||Novel methods for treating neurodegenerative diseases|
|Abstract:||The instant invention is novel uses of known cyclic amino acids. Such compounds as gabapentin are used for treating neurodegenerative disorders, perinatal asphyxia, status epilepticus, Alzheimer's Hungington's, Parkinson's, and Amyotrophic Lateral Sclerosis.|
|Inventor(s):||Woodruff; Geoffrey N. (Herts, GB)|
|Assignee:||Warner-Lambert Company (Morris Plains, NJ)|
1. A method for treating neurodegenerative diseases which comprises administering a therapeutically effective amount of a compound of formula ##STR2## wherein R.sub.1 is hydrogen or a
lower alkyl and n is 4, 5, or 6 or a pharmaceutically acceptable salt thereof, in unit dosage form, to a mammal in need of said treatment.
2. A method according to claim 1 wherein the neurodegenerative disease is stroke.
3. A method according to claim 1 wherein the degenerative disease is Alzheimer's disease.
4. A method according to claim 1 wherein the degenerative disease is Huntington's disease.
5. A method according to claim 1 wherein the degenerative disease is Amyotrophic Lateral Sclerosis.
6. A method according to claim 1 wherein the degenerative disease is Parkinson's disease.
7. A method according to claim 1 wherein the compound is gabapentin or a pharmaceutically acceptable salt thereof.
8. A method according to claim 1 wherein an individual dose is 5 mg to 50 mg parenterally or 50 to 600 mg enterally of the compound or a pharmaceutically acceptable salt thereof is administered.
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