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Summary for Patent: 4,988,731
|Title:||Sodium hydrogen divalproate oligomer|
|Abstract:||This invention concerns certain diethyl- or dipropylacetic acid salts of sodium valproate which have physiological properties similar to those of valproic acid or sodium valproate but show highly superior stability characteristics.|
|Inventor(s):||Meade; Edwin M. (Duncan, CA)|
|Assignee:||Abbott Laboratories (Abbott Park, IL)|
1. An oligomer having a 1:1 molar ratio of sodium valproate and valproic acid of the unit formula, (CH.sub.3 CH.sub.2 CH.sub.2).sub.2 CHCO.sub.2 Na/(CH.sub.3 CH.sub.2 CH.sub.2).sub.2
CHCO.sub.2 H, and containing about 4 such units.
2. An oral pharmaceutical dosage form for treating the symptoms of epileptic seizures or convulsions, containing as the active principal an oligomer having a 1:1 molar ratio of sodium valproate and valproic acid of the unit formula, (CH.sub.3 CH.sub.2 CH.sub.2).sub.2 CHCO.sub.2 Na/(CH.sub.3 CH.sub.2 CH.sub.2).sub.2 CHCO.sub.2 H, and containing about 4 such units.
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