|Title:||Optical isomer of an imidazole derivative medetomidine as an alpha-2-receptor agonist|
|Abstract:||The separated d and l enantiomers of medetomidine and their salts are selective and potent .alpha..sub.2 -receptor agonists.|
|Inventor(s):||Karjalainen; Arto J. (Oulu, FI), Virtanen; Raimo E. (Rusko, FI), Savolainen; Eino J. (Oulu, FI)|
|Assignee:||Farmos Yhtyma Oy (Turku, FI)|
1. The d enantiomer of medetomidine or a non-toxic pharmaceutically acceptable acid addition salt thereof.
2. A pharmaceutical composition suitable for use in a method of sedation/analgesia or treatment of anxiety or hypertension comprising the d-enantiomer of medetomidine or a non-toxic pharmaceutically acceptable acid addition salt thereof in an amount sufficient to produce the desired effect in association with a pharmaceutical carrier.
3. A method of sedation/analgesia or treatment of anxiety or hypertension by administration to a subject of an effective amount of an enantiomer according to claim 1.
4. A method of sedation/analgesia or treatment of anxiety or hypertension by administration to a subject of an effective amount of a composition according to claim 2.
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