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Last Updated: December 15, 2025

Claims for Patent: 4,863,743

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Summary for Patent: 4,863,743

Title:	Controlled release potassium chloride
Abstract:	A controlled release potassium chloride tablet is disclosed which is comprised of potassium chloride crystals having a mesh size of about 30 to about 50 mesh which are coated with a coating material comprised of ethylcellulose and hydroxypropylcellulose. The coated crystals form micro pellets which then can be compressed into tablets. The tablets disintegrate rapidly in an aqueous environment thus assuring a more uniform dissolution of the active component as compared with other types of controlled release potassium chloride dosage formulations. The distribution of the potassium chloride micro pellets over a wide surface area in the gastrointestinal mucosa aids in reducing the risk of gastrointestinal lesions. The formation of the coated micro pellets which disperse quickly upon contact with aqueous environment allow for the repeated chronic oral administration of a relatively large dose of potassium chloride (20 mEq).
Inventor(s):	Charles Hsiao, Chi T. Chou
Assignee:	Key Pharmaceuticals Inc
Application Number:	US06/830,981
Patent Claims:

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