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|Title:||Treatment of human viral infection|
|Abstract:||Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof. Also disclosed is the use of 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.|
|Inventor(s):||Rideout; Janet L. (Raleigh, NC), Barry; David W. (Chapel Hill, NC), Lehrman; Sandra N. (Durham, NC), St. Clair; Martha H. (Durham, NC), Furman; Phillip A. (Durham, NC)|
|Assignee:||Burroughs Wellcome Co. (Research Triangle Park, NC)|
1. A pharmaceutical preparation comprising a capsule containing 5 to 500 mg of 3'-azido-3'-deoxythymidine.
2. The capsule according to claim 1 containing 10 to 200 mg of 3'-azido-3'-deoxythymidine.
3. The capsule according to claim 1 containing 20 to 100 mg at 3'-azido-3'-deoxythymidine.
4. A tablet for oral administration containing 5 to 500 mg of 3'-azido-3'-deoxythymidine and a pharmaceutically acceptable solid carrier therefor.
5. A tablet according to claim 4 containing 10 to 200 mg of 3'-azido-3'-deoxythymidine.
6. A tablet according to claim 4 containing 20 to 100 mg of 3'-azido-3'-deoxythymidine.
7. A pharmaceutical preparation comprising a capsule containing 5 to 500 mg of a pharmaceutically acceptable salt of 3'-azido-3'-deoxythymidine.
8. A tablet for oral administration containing 5 to 500 mg of a pharmaceutically acceptable salt of 3'-azido-3'-deoxythymidine.
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