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Generated: August 20, 2017

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Title: Treatment of Parkinsons disease
Abstract:The present invention relates to the use of certain indolone derivatives in particular, 4-(2-di-n-propyl-aminoethyl)-2-(3H)-indolone in a method of treatment of Parkinsons disease.
Inventor(s): Owen; David A. A. (Welwyn Garden City, GB2)
Assignee: Smith Kline & French Laboratories Limited (Welwyn Garden City, GB2)
Application Number:07/196,653
Patent Claims: 1. A method of treatment of Parkinsons Disease which comprises administering an effective non-toxic amount for the treatment of Parkinsons Disease of a compound of the following structure: ##STR2## in which each group R is hydrogen or C.sub.1-4 alkyl;

R.sup.1 and R.sup.2 are each hydrogen or C.sub.1-4 alkyl;

R.sup.3 is hydrogen or hydroxy; and

n is 1 to 3;

or a pharmaceutically acceptable salt thereof to a subject in need thereof.

2. A method of treatment of Parkinsons Disease which comprises administering an effective non-toxic amount for the treatment of Parkinsons Disease of 4-(2-di-n-propylaminoethyl)-2-(3H)-indolone to a subject in need thereof.

3. A method of treatment of Parkinsons Disease which comprises administering an effective non-toxic amount for the treatment of Parkinsons Disease of 4-(2-di-n-propylaminoethyl)-2-(3H)-indolone hydrochloride to a subject in need thereof.
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Serving 500+ biopharmaceutical companies globally:

Medtronic
Express Scripts
Fuji
Cerilliant
Fish and Richardson
AstraZeneca
Boehringer Ingelheim
Deloitte
UBS
Citi

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