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|Title:||Pediatric ibuprofen compositions|
|Abstract:||A pediatric ibuprofen composition is provided wherein the ibuprofen remains in suspension and wherein the bitter taste of ibuprofen is masked, the primary suspending agents being xanthan gum, microcrystalline cellulose, sodium carboxymelthylcellulose and polysorbate, and the primary taste masking agents being sucrose and sorbitol solution.|
|Inventor(s):||Mody; Dhiraj S. (Hammonton, NJ), Mogavero; Annabelle (Deptford, NJ)|
|Assignee:||American Home Products Corporation (Del.) (New York, NY)|
1. A taste neutral pediatric ibuprofen composition containing about 1% to about 2% weight ibuprofen by volume of the total composition comprising a primary suspension stabilizing
combination of ingredients and a primary taste masking combination of ingredients, the suspension stabilizing combination of ingredients comprising about 1.25% to about 1.5% weight suspension stabilizing combination by volume of the total composition and
consisting essentially of xanthan gum, microcrystalline cellulose, sodium carboxymethylcellulose and polysorbate 80, the taste masking combination comprising about 55% to about 75% weight taste masking combination by volume of the total composition and
consisting essentially of sucrose and sorbitol solution, the composition also containing citric acid as a flavor enhancer in an amount sufficient to adjust the pH to about 3.5 and 5 and water qs to 100% by volume of the composition.
2. The pediatric ibuprofen composition of claim 1 also containing flavoring agents and having an ibuprofen concentration of about 50 mg to about 100 mg per 5 ml of composition.
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