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Serving hundreds of leading biopharmaceutical companies globally:

US Army
Harvard Business School
Johnson and Johnson

Generated: April 23, 2018

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Claims for Patent: 4,731,478

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Summary for Patent: 4,731,478
Title: Sulfamoyl-substituted phenethylamine derivatives, their preparation, and pharmaceutical compositions, containing them
Abstract:A novel process is provided for the preparation of optical isomers of certain sulfamoyl-substituted phenethylamine derivatives which exhibit .alpha.-adrenergic blocking agents which can be used for various treatments such as for the treatment of congestive heart failure.
Inventor(s): Niigata; Kunihiro (Saitama, JP), Fujikura; Takashi (Saitama, JP)
Assignee: Yamanouchi Pharmaceutical Co., Ltd. (Tokyo, JP)
Application Number:06/803,204
Patent Claims: 1. Optically active 5-{2-[2-(2-ethoxyphenoxy)ethyl-amino]-2-methylethyl}-2-methoxybenzenesulfo namide.

2. The [-] isomer of 5-{2-[2-(2-ethoxyphenoxy)ethyl-amino]-2-methylethyl}-2-methoxybenzenesulfo namide.

3. A pharmaceutical composition comprising an .alpha.-adrenergic blocking effective amount of the optically active compound of claim 1, and a pharmaceutically acceptable carrier.

4. The pharmaceutical composition of claim 3, wherein the optically active compound is the [-] isomer of 5-{2-[2-(2-ethoxyphenoxy)ethylamino]-2-methylethyl}-2-methoxybenzenesulfon amide.

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Serving hundreds of leading biopharmaceutical companies globally:

Boehringer Ingelheim
US Army
Argus Health

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