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Claims for Patent: 4,673,563

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Claims for Patent: 4,673,563

Title: Adenosine in the treatment of supraventricular tachycardia
Abstract:A method of diagnosing and treating arrhythmias caused by re-entry in the A-V node by administering to a human or animal an effective amount of adenosine that restores normal sinus rhythm.
Inventor(s): Berne; Robert M. (Charlottesville, VA), Belardinelli; Luiz (Charlottesville, VA), Rubio; Rafael (Charlottesville, VA)
Assignee: The University of Virginia Alumni Patents Foundation (Charlottesville, VA)
Application Number:06/721,122
Patent Claims: 1. A method of treating supraventricular tachycardia caused by re-entry in the AV node, comprising the steps of:

(a) administering intravenously to a human afflicted with the tachycardia, 0.01-0.25 mg/kg of body weight of adenosine sufficient to restore normal rhythm.

2. The method of claim 1, wherein said tachycardia is Wolff-Parkinson-White syndrome.

3. The method of claim 1, wherein said tachycardia is reciprocating junctional tachycardia.

4. The method of claim 1, wherein said amount is 1-8 mg.

5. The method of claim 1, wherein said amount is about 0.06 mg/kg.

6. A method of diagnosing supraventricular tachycardia caused by re-entry in the AV node, comprising the steps of:

(a) administering intravenously to a human afflicated with the tachycardia 0.01-0.25 mg/kg of body weight of adenosine;

(b) monitoring the heart beat of said human for restoration of normal sinus rhythm; and

(c) determining the existence of the tachycardia.

7. The method of claim 6, wherein said tachycardia is Wolff-Parkinson-White syndrome.

8. The method of claim 6, wherein said tachycardia is reciprocating junctional tachycardia.

9. The method of claim 6, wherein said amount is 1-8 mg.

10. The method of claim 6, wherein said amount is about 0.06 mg/kg.
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