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Claims for Patent: 4,665,062

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Claims for Patent: 4,665,062

Title: Method for combating virus infection
Abstract:A method for the selective treatment of virus infections in animals and man and a method of treating cancer caused by viruses, comprising administering to a host so infected a therapeutically effective amount of phosphonoformic acid or a physiologically acceptable salt thereof.
Inventor(s): Eriksson; Bertil F. H. (Sodertalje, SE), Helgstrand; Ake J. E. (Enhorna, SE), Misiorny; Alfons (Bandhagen, SE), Stening; Goran B. (Sodertalje, SE), Stridh; Stig A. (Sodertalje, SE)
Assignee: Astra Lakemedel Aktiebolag (Sodertalje, SE)
Application Number:06/404,295
Patent Claims: 1. A pharmaceutical preparation effective for treating virus infections in animals or man packaged in a dosage unit form suitable for use in topical administration to humans comprising as an active ingredient about 0.05% to about 20% by weight of the preparation of the compound of the formula: ##STR4## or a physiologically acceptable salt thereof, together with a physiologically acceptable carrier said carrier being substantially free of pharmaceutically unacceptable impurities and thus suitable for topical administration to humans.

2. A pharmaceutical preparation effective for treating virus infections in animals or man in dosage unit form comprising as an active ingredient about 0.05% to about 20% by weight of the preparation of the compound of the formula: ##STR5## or a physiologically acceptable salt thereof, together with a physiologically acceptable sterile carrier therefor, said sterile carrier being substantially free of pharmaceutically unacceptable impurities and thus being suitable for administration to humans.

3. A pharmaceutical preparation according to claim 2 wherein said compound is a tri-sodium salt of phosphonoformic acid.

4. A pharmaceutical preparation as described in claim 1 wherein the preparations is in the form selected from the group consisting of a solution, an ointment, a gel, a suspension and a cream.

5. A pharmaceutical preparation according to claim 4 wherein the preparation is a cream and also contains an absorption promoter.

6. A pharmaceutical preparation according to claims 1 or 4 wherein said compound is a tri-sodium salt of phosphonoformic acid.
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