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Serving hundreds of leading biopharmaceutical companies globally:

Daiichi Sankyo
US Department of Justice

Generated: June 22, 2018

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Claims for Patent: 4,661,493

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Summary for Patent: 4,661,493
Title: Tioconazole and related compounds for control of Herpes simplex virus
Abstract:Topical vaginal forms of tioconazole and related antimicrobic compounds, especially miconazole, econazole, clotrimazole, butaconazole and ketoconazole, are useful for the control (chemotherapeutic and chemoprophylactic) of Herpes virus infections.
Inventor(s): Gibbs; David L. (New York, NY)
Assignee: Pfizer Inc. (New York, NY)
Application Number:06/837,658
Patent Claims: 1. A method for the treatment of herpetic infections in a human infected thereby which comprises topically applying to the site of said infection an anti-herpetic amount of drug selected from the group consisting of tioconazole, econazole, clotrimazole, ketoconazole, butaconazole or a pharmaceutically acceptable acid addition salt thereof.

2. A method according to claim 1 wherein the drug is applied in the form of a cream or ointment comprising from about 1% to about 10% of said drug.

3. A method according to claim 2 wherein the drug is administered intravaginally.

4. The method according to claim 3 wherein the drug is tioconazole.

5. The method according to claim 3 wherein the drug is econazole.

6. The method according to claim 3 wherein the drug is clotrimazole.

7. The method according to claim 3 wherein the drug is butaconazole.

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