Claims for Patent: 4,631,286
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Summary for Patent: 4,631,286
| Title: | 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds |
| Abstract: | There are disclosed compounds having the formula ##STR1## wherein X is hydrogen, loweralkyl, loweralkoxy, halogen, hydroxy, nitro, NHCOR2 wherein R2 is loweralkyl, or a group of the formula NR3 R4 wherein R3 and R4 are independently hydrogen or loweralkyl; R and R1 are independently hydrogen, loweralkyl, phenylloweralkyl, phenylloweralkyl in which the phenyl group is substituted by one or more loweralkyl, loweralkoxy, halogen, hydroxy or trifluoromethyl, diphenylloweralkyl or diphenylloweralkyl in which one or both phenyl groups are substituted by one or more loweralkyl, loweralkoxy, halogen, hydroxy or trifluoromethyl; Y is C═O or CR5 OH wherein R5 is hydrogen or loweralkyl; Z is CH2 or C═CR6 R7 wherein R6 and R7 are independently hydrogen or loweralkyl; or Y and Z taken together is CR5 ═CH wherein CR5 and CH correspond to Y and Z respectively; an optical antipode thereof, or a pharmaceutically acceptable acid addition salt thereof, which are useful for enhancing memory, methods for synthesizing them, and pharmaceutical compositions comprising an effective memory enhancing amount of such a compound. |
| Inventor(s): | Gregory M. Shutske, Frank A. Pierrat |
| Assignee: | Aventis Pharmaceuticals Inc |
| Application Number: | US06/664,731 |
| Patent Claims: |
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ISSN: 2162-2639
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