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Generated: April 24, 2017

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Claims for Patent: 4,619,921

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Claims for Patent: 4,619,921

Title: Polyhalogeno-steroids
Abstract:Novel 6.alpha.,9.alpha.,21-trihalogeno-11.beta.-hydroxy-16.alpha. or 16.beta.-methyl-17.alpha.-propionyloxy-pregn-4-ene-3,20-dione compounds of the formula ##STR1## in which X represents chlorine or flourine, R represents the group --CH.sub.2 CH--, --CH.dbd.CH-- or --CH.dbd.CCl--, the chlorine atom being in the positon 2 of the steroid numbering, and in which the 16-methyl radical is .alpha.- or .beta.-oriented, are useful pharmaceuticals, especially anti-inflammatory agents for topical administration.
Inventor(s): Kalvoda; Jaroslav (Binningen, CH), Anner; Georg (Basel, CH)
Assignee: Ciba-Geigy Corporation (Ardsley, NY)
Application Number:06/601,746
Patent Claims: 1. A compound which is 21-chloro-6.alpha.,9.alpha.-difluoro-11.beta.,17.alpha.-dihydroxy-16.beta. -methyl-pregna-1,4-diene-3,20-dione 17-propionate.

2. An anti-inflammatory pharmaceutical composition comprising an anti-inflammatory effective amount of the compound of claim 1 and a pharmaceutically acceptable carrier.
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