Deep knowledge on
small-molecule drugs and
the 110,000 global patents
Find generic entry opportunities
Manage your formulary budget
Proactively manage your pharmacy inventory
Drug patents …
… from Kazakhstan to Kalamazoo
Anticipate generic drug launch
Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing
|Title:||Local anesthetic mixture for topical application, process for its preparation, as well as method for obtaining local anesthesia|
|Abstract:||The present invention relates to pharmacological active preparations, especially local anesthetic preparations and deals with the problem of i a obtaining a solution of a local anesthetic agent in the form of its base, where the concentration is higher than otherwise possible. This problem has been dissolved according to the present invention thereby that one local anesthetic agent in the form of its base and as such having a melting point of 30.degree. to 50.degree. C., preferably prilocaine or tetracaine, is provided with one other local anesthetic agent in the form of its base and as such having a melting point of above 30.degree. C., preferably above 40.degree. C., preferably bensocaine, lidocaine, bupivacaine, mepivacaine, etidocaine or tetracaine which agents when brought and heated together form a homogenous oil having a melting of preferably below 40.degree. C., more preferably below 25.degree. C.|
|Inventor(s):||Broberg; Berndt F. J. (Sodertalje, SE), Evers; Hans C. A. (Sodertalje, SE)|
|Assignee:||Astra Lakemedel Aktiebolag (SE)|
1. A locally active anesthetic agent comprising paper embedded with a homogeneous oil which is useful for topical application, consisting essentially of prilocaine in the form of its
base in admixture with lidocaine, in the form of its base in a weight ratio of 42:58 to 80:20 such that the resulting mixture is a homogeneous oil which has a melting point of below 40.degree. C.
2. A method of obtaining local anesthesia in mammals by way of topical application, which comprises administering to a patient a paper embedded with an anesthetically effective amount of a combination of prilocaine in the form of its base in admixture with lidocaine in the form of its base in a weight ratio of 42:58 to 80:20 such that the resulting mixture is a homogeneous oil which has a melting point of below 40.degree. C.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.