|Title:||Ophthalmic use of norfloxacin and related antibiotics|
|Abstract:||Norfloxacin and related antibiotics are useful in the treatment of ocular infections by topical administration.|
|Inventor(s):||Katz; Irving M. (Doylestown, PA)|
|Assignee:||Merck & Co., Inc. (Rahway, NJ)|
1. A method of treating ocular bacterial infections which comprises topical ocular administration to an infected eye, of 0.015-1.5 mg of an antibiotic selected from
norfloxacin, ofloxacin, pefloxacin, AT-2266 and Bayer 09867, hydrates or ophthalmologically acceptable salts thereof.
2. The method of claim 1 wherein the antibiotic is norfloxacin, a hydrate or ophthalmologically acceptable salt thereof.
3. The method of claim 2 wherein the norfloxacin is administered as an aqueous solution.
4. The method of claim 1 wherein the carrier is a clear physiologically-acceptable liquid which forms a semi-solid gel at human body temperatures.