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Claims for Patent: 4,522,807

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Claims for Patent: 4,522,807

Title: Substantive topical compositions
Abstract:A highly substantive topical composition in the form of an oil-in-water emulsion containing an octadecene-1/maleic anhydride copolymer.
Inventor(s): Kaplan; Carl (Memphis, TN)
Assignee: Plough, Inc. (Memphis, TN)
Application Number:06/496,032
Patent Claims: 1. A dermatologically compatible, highly substantive sunscreening oil-in-water emulsion composition comprising 0.1 to 5% octadecene-1/maleic anhydride copolymer having a molecular weight of 4,000 to 100,000, an effective sunscreening amount of a sunscreening agent, an oil, from 40 to 95% water and having a pH of 6 to 10.

2. A composition according to claim 1 wherein the concentration of said copolymer is 0.3 to 3.0 percent.

3. A composition according to claim 1 in which said copolymer has a molecular weight of about 40,000 to 60,000.

4. A composition according to claim 3 in which the molecular weight of said copolymer is about 50,000.

5. A composition according to claim 1 in which the monomers of said copolymer are present in substantially a 1:2 to 2:1 molar ratio.

6. A composition according to claim 5 in which said monomers are present in substantially a 1:1 molar ratio.

7. A composition according to claim 6 wherein said copolymer has a melting point range of 110.degree.-120.degree..

8. A composition according to claim 1 in which the composition is an anionic emulsion.

9. A composition according to claim 1 in which the sunscreening agent comprises homomenthyl salicylate.

10. A composition according to claim 1 in which the sunscreening agent comprises octyldimethyl PABA.

11. A composition according to claim 1 in which the sunscreening agent comprises octyl methoxycinnamate.

12. A composition according to claim 1 in which the pH of said composition is 7 to 9.

13. A method of increasing the substantivity of an oil-in-water sunscreening emulsion containing an oil, a sunscreening agent, and 40 to 95% water by incorporating therein 0.1 to 5% of octadecene-1/maleic anhydride copolymer having a molecular weight of 4,000 to 100,000 wherein the pH is 6 to 10.

14. The method of claim 13 wherein the sunscreen agent is selected from the group consisting of octyl dimethyl PABA, homomenthyl salicylate, benzophenone-3, and octyl methoxycinnimate.
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