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Summary for Patent: 4,508,726
|Title:||Treatment of panic disorders with alprazolam|
|Abstract:||Therapeutic process for treating panic disorders in humans comprising, the systemic administration of a 1-methyl-6-phenyl-8-chloro-4H-s-triazolo[4,3-a][1,4]benzodiazepine including the N-oxides and pharmacologically acceptable acid addition salts thereof in combination with a pharmaceutical carrier.|
|Inventor(s):||Coleman; James H. (Cumberland, RI)|
|Assignee:||The Upjohn Company (Kalamazoo, MI)|
1. A process for preventing or treating panic attacks comprising the administration to a human subject susceptible to panic attacks, in unit dosage form, from about 0.01 mg to about 0.4
mg/kg body weight of 8-chloro-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine or the pharmacologically acceptable acid addition salt or a (5) N-oxide thereof in association with a pharmaceutical carrier.
2. The process of claim 1 wherein the 8-chloro-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine is in the form of the (5) N-oxide.
3. The process of claim 1 wherein the 8-chloro-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine is in the form of the free base.
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