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Serving leading biopharmaceutical companies globally:

US Department of Justice
Accenture
Fish and Richardson
Colorcon
AstraZeneca
Baxter
Express Scripts
McKesson
Cipla
Daiichi Sankyo

Generated: February 24, 2018

DrugPatentWatch Database Preview

Claims for Patent: 4,459,310

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Summary for Patent: 4,459,310
Title: Method for cholesterol lowering
Abstract:This invention encompasses a new use for 16-loweralkyl-16-hydroxy prostaglandins such as misoprostol. This class of prostaglandin has been found useful in lowering cholesterol blood levels in patients with hypercholesterolemia.
Inventor(s): Dajani; Esam Z. (Long Grove, IL)
Assignee: G.D. Searle & Co. (Skokie, IL)
Application Number:06/508,373
Patent Claims: 1. A method for lowering elevated cholesterol levels in humans comprising administering to a human having elevated cholesterol an effective cholesterol lowering amount of a prostaglandin of the formula ##STR5## wherein R.sub.1, is hydrogen or lower alkyl, R.sub.2 and R.sub.3 are hydrogen or loweralkanoyl, R.sub.4 is lower alkyl, and x is --CH.sub.2 --CH.sub.2 -- or --CH.dbd.CH--.

2. A method according to claim 1 for lowering elevated cholesterol levels in humans comprising administering to a human having elevated cholesterol an effective cholesterol lowering amount of a prostaglandin of the formula ##STR6##

3. A method according to claim 1 for lowering elevated cholesterol levels in humans comprising administering to a human having elevated cholesterol an effective cholesterol lowering amount of misoprostol.

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Argus Health
Covington
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Julphar
Medtronic
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Deloitte
Federal Trade Commission

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